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Therefore, maintaining cell wall integrity by regulation of cell wall hydrolysing/modifying enzymes such as pectin methyl esterase would be prime contributary to sustain the root apical viability against Al stress

Its main effects are already well-understood, and that opens the door to multi-peptide study designs

Moreover, other important chondrocyte-specific proteins, such as Cartilage Oligomeric Matrix Protein, Aggrecan and Cartilage-associated Protein, are produced and secreted at significant levels by chondrocytes at P6

The main efficacy outcome measures in the KEYNOTE-177 trial were progression-free survival (PFS) and overall survival (OS), with median PFS demonstrated to be 16.5 months (95% confidence interval [CI], 5.4, 32.4) in the pembrolizumab arm and 8.2 months in the chemotherapy arm (95% CI, 6.1, 10.2)